Synthesis, characterization and applications of Organomecury(II) pyrrolidine-N-thiohydrazide complexes

Abstract

The complexes of organomercury(II) with pyrrolidine-N-thiohydrazide of the type RHg(L)Cl where[R=C₆H₅ (phenyl), p-ClC₆H₄ (p-chlorophenyl), p-BrC₆H₄ (p-bromophenyl), o-, p-HOC₆H_4, (o-,p-hydroxyphenyl)_, L = pyrrolidine-N-thiohydrazide, have been synthesized and characterized by elemental analysis, IR,¹H-NMR and electronic spectral analysis. Thermogravimetric and differential thermal analytical curves are used to calculate thermodynamic parameters and variations in these parameters have been correlated with complex structural parameters. All complexes were tested in vitro for their antibacterial activity against Gram-negative bacteria, namely, Escherichia coli, Zymomonas mobilis and against two pathogenic fungal strains, namely, Aspergillus niger and Cerveleria.